1.
Chem Commun (Camb)
; 60(32): 4362-4365, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38563154
RESUMO
A selective intermolecular Schmidt reaction of equilibrating hydroxyalkyl allylic azides is reported to afford N-hydroxyalk-1-en-3-yl lactams in modest to high yields. For prochiral and chiral ketones, modest to high 1,5-diastereoselectivity was achieved, and the mechanistic analysis is supported by DFT calculation.